Caspase-11 promotes renal fibrosis by stimulating IL-1β maturation via activating caspase-1
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چکیده
منابع مشابه
Oligomerized CARD16 promotes caspase-1 assembly and IL-1β processing
Increasing evidence indicates that caspase recruitment domain (CARD)-mediated caspase-1 (CASP1) assembly is an essential process for its activation and subsequent interleukin (IL)-1β release, leading to the initiation of inflammation. Both CARD16 and CARD17 were previously reported as inhibitory homologs of CASP1; however, their molecular function remains unclear. Here, we identified that oligo...
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ژورنال
عنوان ژورنال: Acta Pharmacologica Sinica
سال: 2018
ISSN: 1671-4083,1745-7254
DOI: 10.1038/s41401-018-0177-5